Correlation of Ejection Fraction, Diastolic Function and Left Ventricular Volume Index Preoperative with Major Cardiovascular Events During Postoperative Treatment of Coronary Artery Bypass Graft
I Gede Angga Yogiswara1, Ida Bagus Rangga Wibhuti1, I Komang Adhi Parama Harta2
Abstract
Background: Technological advances in coronary artery bypass graft surgery can improve patient outcomes after CABG surgery. Echocardiography parameters indicate left ventricular function. In CABG, left ventricular function plays an important role in the occurrence of major cardiovascular events (MACE) after CABG. This study assesses the relationship between ejection fraction, diastolic function, and preoperative left ventricular index volume with MACE during post-CABG care. Methods: Retrospective cohort study. Independent variables are ejection fraction, diastolic function, and left ventricular volume index. MACE during treatment is cardiovascular death, cardiogenic shock, acute heart failure, arrhythmia, and myocardial infarction. Results: A total of 79 samples were enrolled in this study. There were 36 patients (45.6%) with EF <45%, 67 patients (84.8%) with diastolic dysfunction, and 39 patients (49.3%) with an index volume > 64 ml/m2. After follow-up during treatment, 23 patients (29.1%) experienced MACE. The cut-off value for EF was 45% (AUC 0.255; 95% CI 0.14 – 0.37; p 0.001, while the cut-off value for LVVi was 67 ml/m2 (AUC 0.680; 95% CI 0.6 – 0.8; p 0.012). Cox regression analysis showed EF < 45% (adjusted HR 3.2; 95% CI 1.2 – 8.1; p = 0.016), diastolic dysfunction (adjusted HARI 0.7; 95% CI 0.1 – 6.9; p = 0.769) and index volume > 67 ml/m2 (adjusted HR 1.0; 95% CI 0.3 – 3.1; p = 0.993). Conclusion: Ejection fraction < 45% is an independent predictor of MACE during postoperative care of CABG. Diastolic dysfunction and volume index > 67 ml/m2 are not significant enough as predictors of MACE during postoperative care of CABG.
Keywords
ejection fraction; diastolic function; volume index; CABG; MACE
Cite This Article
Yogiswara, I. G. A., Wibhuti, I. B. R., Harta, I. K. A. P. (2024). Correlation of Ejection Fraction, Diastolic Function and Left Ventricular Volume Index Preoperative with Major Cardiovascular Events During Postoperative Treatment of Coronary Artery Bypass Graft. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 4: Jul-Aug 2024, Pages 832-843, URL: https://www.ijscia.com/wp-content/uploads/2024/08/Volume5-Issue4-Jul-Aug-No.655-832-843.pdf
Volume 5 | Issue 4: Jul-Aug 2024
