High Platelet to Lymphocyte Ratio (PLR) Associated with High Q-Sofa in Multi-Trauma Patients at RSUP Prof Dr I.G.N.G Ngoerah Hospital Denpasar
I Gede Wahyu Dwi Pradita1, I Ketut Wiargitha2, and Tjokorda Gde Bagus Mahadewa3
Abstract
Background: Trauma is one of the world’s major health problems; in 2013, 56.2 million patients were hospitalized, and globally, 8 million people died from trauma. Traumatic injury can cause changes in immune function, which can lead to the activation of proinflammatory cytokines known as SIRS. In addition to the immune response in addition to SIRS, platelets also play an important role in trauma; platelets play a key role in hemostasis. A simple clinical screening tool that performs very well in identifying adult patients with suspected infection is called qSOFA. Apart from that, a new score, namely PLR, was also found to be able to predict the severity of trauma more quickly. Therefore, PLR is thought to be able to predict the severity of a trauma that results in SIRS using qSOFA. Objective: To determine if the high PLR value is significantly related to the improvement of the qSOFA score in multi-trauma cases. Method: This type of study is a cross-sectional study. The subjects of this study totaled 45, which were divided based on the data of PLR value variables, namely ≤ 200 and > 200, and qSOFA score variables, namely ≥2 and <2. Results: The Spearman test conducted in the study obtained a value of p = 0.001. In addition, the correlation value between PLR and qSOFA variables was found to be 0.444 in the contingency coefficient test and 0.469 in the Spearman test. Conclusion: Both variables show a significant relationship between PLR and qSOFA, so they can be used to assess each variable. However, the correlation shown by these two variables is quite low, so further research can be done to confirm this condition.
Keywords
multi-trauma; SIRS; qSOFA; PLR; sepsis.
Cite This Article
Praita, I. G. W. D., Wiargitha, I. K., Mahadewa, T. G. B. (2024). High Platelet to Lymphocyte Ratio (PLR) Associated with High Q-Sofa in Multi-Trauma Patients at RSUP Prof Dr I.G.N.G Ngoerah Hospital Denpasar. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1066-1074, URL: https://www.ijscia.com/wp-content/uploads/2024/11/Volume5-Issue6-Nov-Dec-No.690-1066-1074.pdf
Volume 5 | Issue 6: Nov – Dec 2024
