The Correlation Between Age of Diagnosis and Quality of Life in Children with Congenital Hypothyroidism: A Cross Sectional Study in A Limited Resource Setting
Dhinda Adilia Zulia Rahma1, Nur Rochmah2,3*, Sony Wibisono Mudjanarko4,5, and Ema Qurnianingsih6
Abstract
Background and Objectives: Thyroid hormones have a significant impact on how the brain develops. The quality of life is greatly impacted by early diagnosis. Analyzing the correlation between the age of diagnosis and quality of life in children with congenital hypothyroidism in a setting with limited resources was the aim of this study. Materials and Methods: A cross-sectional study was performed on 31 children with congenital hypothyroidism who were still under routine control from August 2023 to February 2024. The generic Pediatric Quality of Life Inventory (PedsQL) scale was used to measure quality of life, while age at diagnosis was obtained from the patient’s medical record data. The normality test was performed and followed by Spearman analysis. Result: A total of 15 out of 31 children were aged between 2-4 years old. There were 15 respondents who were successfully diagnosed <6 months. There were 14 children who were diagnosed with central hypothyroidism. The average PedsQL score of 16 children was in the poor category (0-76). Age of diagnosis and quality of life showed abnormal distribution with Asymp. Sig (2-tailed) < 0.05. There was a correlation between age of diagnosis and quality of life (α=0.05, p=0.042, p<α). The Spearman correlation was in the negative distribution (-0,366), so the correlation between age of diagnosis and quality of life was inversely proportional. Conclusion: In children with congenital hypothyroidism, the age of diagnosis was associated with the quality of life overall, but was not significantly with each quality of life sector.
Keywords
congenital hypothyroidism; child; age of diagnosis; quality of life.
Cite This Article
Rahma, D. A. Z., Roch, N., Mudjanarko, S. W., Qurnianingsih, E. (2024). The Correlation Between Age of Diagnosis and Quality of Life in Children with Congenital Hypothyroidism: A Cross Sectional Study in A Limited Resource Setting. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1075-1080, URL: https://www.ijscia.com/wp-content/uploads/2024/11/Volume5-Issue6-Nov-Dec-No.691-1075-1080.pdf
Volume 5 | Issue 6: Nov – Dec 2024
