The Analysis of Predictors of Limb Amputation in Chronic Limb Ischemia (CLI) Patients at Prof. I.G.N.G. Ngoerah Hospital Denpasar

I Putu Kumara Jaya^1*, IGAB Krisna Wibawa², Tjokorda Gde Bagus Mahadewa³

Abstract

Background: Chronic limb ischemia is a condition where there is an interruption in arterial blood flow that has lasted for 14 days or more. CLI is one of the peripheral arterial diseases with the highest incidence. CLI can progress to a more serious stage and even cause severe morbidity in the form of amputation and death. Although CLI treatment is well developed, the predictors of amputation in CLI patients are not fully understood, especially in Indonesia. Some factors that may be related to the predictors of amputation in patients with CLI are CHF, INR, NLR, ABI, and DVT. Objective: This study aims to identify predictors of amputation in CLI patients who have received treatment at Prof. I.G.N.G Ngoerah Hospital, Denpasar. Method: This study used a retrospective cohort research design to determine the predictors of limb amputation in patients with CLI. Data were collected through medical records with a total sample of 46 samples. Result: The results of bivariate analysis showed that high NLR, ABI, CHF, and DVT had a significant correlation with increased amputation risk in CLI patients. The results of multivariate analysis showed that high CHF and NLR increased the risk of amputation in CLI patients, while type 2 DM, hypertension, and PAD were protective factors, although not statistically significant. Conclusion: Chronic heart failure and NLR>2 increased amputation risk by 3.6 and 2.8 times, respectively. The use of these predictors may assist clinicians in making treatment decisions to minimize the risk of amputation in CLI patients.

Keywords

Chronic Limb Ischemia (CLI); predictor; amputation; Neutrophil Lymphocyte Ratio (NLR); Ankle Brachial Index (ABI); Deep Vein Thrombosis (DVT).

Cite This Article

Jaya, I. P. K., Wibawa, IGAB. K., Mahadewa, T. G. B. (2024). The Analysis of Predictors of Limb Amputation in Chronic Limb Ischemia (CLI) Patients at Prof. I.G.N.G. Ngoerah Hospital Denpasar. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1235-1244, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.712-1235-1244.pdf

Volume 5 | Issue 6: Nov – Dec 2024