Correlation between Sperm Analysis Factors and Pregnancy in Post-Varicocele Surgery Patients with Microligation Technique
Agus Eka Wahyudi1*, Gede Wirya Kusuma Duarsa2, Kadek Budi Sentosa2
Abstract
Background: Varicocele is the most common cause of male infertility, with a prevalence of 19-41% in men with primary infertility and 45-81% in men with secondary infertility. However, further research is needed to investigate its impact on postoperative pregnancy outcomes. Methods: This study employed a quantitative research design with a case-control approach to evaluate sperm analysis-related factors influencing pregnancy in patients who underwent varicocelectomy using the microligation technique. Patient data were obtained from medical records at Prof. Dr. IGNG Ngoerah General Hospital and Balimed Denpasar Hospital from 2018 to 2022, with a minimum sample size of 14 individuals in each group based on inclusion and exclusion criteria. Data analysis was conducted using SPSS v21.0 to determine the relationship between sperm analysis and pregnancy occurrence in couples. Results: Significant differences were found in the duration of infertility between the case and control groups (2.76 ± 2.12 vs 1.32 ± 0.62; p=0.017). The cutoff duration of infertility was determined to be 2.5 years with an AUC of 0.678 and was significantly associated with pregnancy occurrence (OR 18.857; p=0.001; 95%CI 2.195 – 181.985). Parameters such as rapid motility, slow motility, morphology, and sperm concentration exhibited significant differences between pre and post-microligation (p<0.05). Multivariate analysis revealed that the history of infertility had a 1,411 times higher impact on sperm quality compared to a shorter duration of infertility (p=0.034). Conclusion: The microligation technique was able to improve sperm analysis parameters postoperatively. However, no significant correlation was observed between these parameters and pregnancy occurrence.
Keywords
microligation; pregnancy; sperm analysis; varicocele surgery.
Cite This Article
Wahyudi, A. E., Duarsa, G. W. K., Sentosa, K. B. (2024). Correlation between Sperm Analysis Factors and Pregnancy in Post-Varicocele Surgery Patients with Microligation Technique. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1245-1251, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.713-1245-1251.pdf
Volume 5 | Issue 6: Nov – Dec 2024
