An Overview of Weight Changes Before and After Chemotherapy for Ovarian Cancer at Dr. Soetomo Hospital Surabaya in the Period 2021-2023

Farras Ariq¹, Jongky Hendro Prajitno^2*

Abstract

Objectives: This study aims to determine body weight changes in ovarian cancer patients before and after receiving first-line chemotherapy treatment. Materials and Methods: This research is a retrospective descriptive study. The study population consisted of ovarian cancer patients who received chemotherapy at Dr. Soetomo General Academic Hospital, Surabaya. The sample included all ovarian cancer patients who received chemotherapy during the period 2021-2023. Data collected included the type of chemotherapy, weight, ovarian cancer stage, duration of chemotherapy, age, and comorbidities. The chemotherapy regimen used was paclitaxel 175 mg/m² and carboplatin AUC5. Results: A total of 206 ovarian cancer patients were analyzed. Most patients who received neoadjuvant chemotherapy experienced weight gain. Specifically, patients who received neoadjuvant chemotherapy mostly experienced weight gain. Weight loss was more common in patients receiving 3 cycles of adjuvant chemotherapy, while weight gain was frequent in those undergoing 4–6 cycles. Of patients who received 6 cycles of adjuvant chemotherapy, 64.52% experienced weight gain, 9.68% maintained their weight, and 25.81% experienced weight loss. The majority of ovarian cancer patients who received chemotherapy were in stage III. The predominant age group was 50-59 years. Additionally, age-specific analysis showed that the highest percentage of weight gain occurred in the 40-49 age group, while the highest percentage of weight loss occurred in the same age group. Conclusion: Significant changes in body weight among ovarian cancer patients undergoing chemotherapy at Dr. Soetomo Hospital, Surabaya during 2021-2023. Monitoring and managing weight changes is crucial for improving treatment outcomes and quality of life.

Keywords

ovarian cancer; chemotherapy; weight changes; paclitaxel; carboplatin.

Cite This Article

Ariq, F., Prajitno, J. H. (2024). An Overview of Weight Changes Before and After Chemotherapy for Ovarian Cancer at Dr. Soetomo Hospital Surabaya in the Period 2021-2023. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1395-1397, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.739-1395-1397.pdf

Volume 5 | Issue 6: Nov – Dec 2024