The Protective Role of Silver Nanoparticles and Centella Asiatica Extract in Hypertension Management: A Literature Review
Sonya Marella Tiomaulan Situmorang1, Rendy Steven Pratama1, Rania Zahra Regita1, Reny I’tishom2*
Abstract
Hypertension remains a leading global health issue, affecting over 1.28 billion adults and necessitating innovative therapeutic strategies. This study explores the synergistic potential of silver nanoparticles (AgNPs) and Centella Asiatica extracts in hypertension management through a comprehensive systematic literature review. AgNPs offer precision and enhanced bioavailability in drug delivery, exhibiting antioxidative and anti-inflammatory properties essential for cardiovascular protection. Similarly, Centella Asiatica, a traditional herbal remedy, provides comparable efficacy to conventional antihypertensive drugs by targeting oxidative stress, modulating the renin-angiotensin system, and enhancing nitric oxide production. Despite their potential, challenges such as nanoparticle toxicity and the need for optimized herbal extraction methods remain critical Experimental evidence supports the efficacy of these interventions in reducing blood pressure and protecting against hypertension-induced organ damage. The integration of nanotechnology and herbal medicine presents a promising, personalized therapeutic paradigm, addressing both the complexity and variability of hypertension pathophysiology. Future research must emphasize safety, precision, and sustainability in developing these innovative approaches. By incorporating advanced nanotechnological methods and traditional medicinal wisdom, this study paves the way for a more holistic and effective hypertension management framework.
Keywords
hypertension; silver nanoparticles; Centella Asiatica; nanotechnology; cardiovascular protection.
Cite This Article
Situmorang, S. M. T., Pratama, R. S., Regita, R. Z., I’tishom, R. (2024). The Protective Role of Silver Nanoparticles and Centella Asiatica Extract in Hypertension Management: A Literature Review. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1440-1447, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.749-1440-1447.pdf
Volume 5 | Issue 6: Nov – Dec 2024
