Hypoallergenic Foods in Pediatric Nutrition: A Comprehensive Review

Utami Dian Putri1, Azwin Mengindra Putera2*, Deasy Fetarayani3, Taufiq Hidayat2

Abstract

Background: Food allergies are a growing concern in pediatric populations, with cow’s milk protein allergy (CMPA) being the most prevalent. CMPA affects 2–3% of children globally and can lead to poor nutritional status, impaired growth, and reduced quality of life. Hypoallergenic foods, particularly extensively hydrolyzed formulas (EHFs) and amino acid-based formulas (AAFs), are essential dietary interventions for managing CMPA and preventing allergy development. Objective: This review evaluates hypoallergenic foods’ efficacy, safety, and clinical applications in pediatric allergy prevention and management. Methods: A systematic literature review was conducted using peer-reviewed articles, clinical studies, and guidelines related to hypoallergenic formulas, their clinical outcomes, and allergy prevention strategies in children. Results: EHFs and AAFs are proven effective in managing cow’s milk protein allergy (CMPA) and improving growth outcomes. EHFs are recommended for mild-to-moderate cases, while AAFs are the standard for severe allergies. Emerging evidence suggests that probiotic-supplemented formulas may enhance tolerance. Clinical guidelines emphasize early intervention in high-risk infants to reduce allergy development. Conclusion: Hypoallergenic foods play a critical role in pediatric allergy management, with EHFs and AAFs as key dietary interventions. Continued research is needed to improve formula composition and long-term outcomes.

Keywords

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Cite This Article

Putri, U. D., Putera, A. M., Fetarayani, D., Hidayat, T. (2024). Hypoallergenic Foods in Pediatric Nutrition: A Comprehensive Review. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1448-1453, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.750-1448-1453.pdf

Volume 5 | Issue 6: Nov – Dec 2024