Potential of Turmeric Rhizome (Curcuma longa) as an antibacterial agent against Staphylococcus aureus: A Lab Experimental Study
Muhammad Mirza Abdul Aziz1, Rebekah Juniati Setiabudi2,3*, Yuani Setiawati4, Kusuma Eko Purwantari4
Abstract
Introduction: Staphylococcus aureus can cause various clinical manifestations in humans. With the rising number of antibiotic-resistant pathogens, the widespread of Staphylococcus aureus is troublesome so new alternative antimicrobial substance is needed. One of the potential substances is turmeric (Curcuma longa) which contains tannins and flavonoids that have been proven to have antibacterial effects. This study evaluated the antibacterial effects of Curcuma longa rhizome extract against Staphylococcus aureus. Methods: This study is a true experimental with a posttest-only control group design using tube dilution and agar dilution methods. Treatment groups are groups of Staphylococcus aureus that were given Curcuma longa extract with concentrations 300, 150, 75, 37.5, 18.75, and 9.375 mg/ml. The replication used in this research was four replications. MIC (Minimum Inhibitory Concentration) was observed visually by comparing the turbidity of the solution before and after incubation at 370C for 24 hours. The MBC (Minimum Bactericidal Concentration) was observed visually by observing the presence of Staphylococcus aureus colonies growth. Results: MIC cannot be observed due to no change in turbidity before and after treatment. Cultures on nutrient agar plates had no colony growth in concentrations of 300, 150, and 75 mg/ml. Thus, the MBC is 75 mg/ml. Conclusion: There is an antibacterial effect of Curcuma longa extracts against Staphylococcus aureus with a Minimum Bactericidal Concentration of 75 mg/ml.
Keywords
antibacterial; Curcuma longa extracts; staphylococcus aureus; antimicrobial activity.
Cite This Article
Aziz, M. M. A., Setiabudi, R. J., Setiawati, Y., Purwantari, K. E. (2025). Potential of Turmeric Rhizome (Curcuma longa) as an antibacterial agent against Staphylococcus aureus: A Lab Experimental Study. International Journal of Scientific Advances (IJSCIA), Volume 6| Issue 1: Jan-Feb 2025, Pages 47-51, URL: https://www.ijscia.com/wp-content/uploads/2025/01/Volume6-Issue1-Jan-Feb-No.821-47-51.pdf
Volume 6 | Issue 1: Jan – Feb 2025
