Comparison Between Culprit-Lesion Only and Complete PCI in Patients with STEMI and Multivessel Disease: A Literature Review

Rasagama Putra Soesanta*, Rifky Alif Novianto

Abstract

Cardiovascular diseases, particularly Coronary Artery Disease (CAD), remain a leading cause of global mortality, with Acute Coronary Syndrome (ACS) being a major manifestation. Among ACS conditions, ST-elevation Myocardial Infarction (STEMI) is associated with significant morbidity and mortality, especially in patients with multivessel coronary artery disease (MVD). Percutaneous coronary intervention (PCI) of the culprit lesion has long been the standard approach for STEMI, but the role of complete revascularization, involving PCI of both the culprit and non-culprit lesions, remains a subject of debate. This literature review compares culprit-lesion-only PCI and complete PCI in patients with STEMI and multivessel disease. Studies show that complete PCI is associated with a significant reduction in cardiovascular death, myocardial infarction, and the need for repeat revascularization, compared to culprit-lesion-only PCI. Furthermore, early complete revascularization, particularly guided by physiology, appears to improve long-term survival and reduce major adverse cardiovascular events. These findings suggest that complete PCI may be the preferred strategy for patients with STEMI and multivessel disease, offering improved prognosis by addressing high-risk coronary plaques early in the disease process.

Keywords

STEMI; Multivessel Disease; Culprit-Only Lesion; Complete PCI.

Cite This Article

Soesanta, R. P., Novianto, R. (2024). Comparison Between Culprit-Lesion Only and Complete PCI in Patients with STEMI and Multivessel Disease: A Literature Review. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1380-1383, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.736-1380-1383.pdf

Volume 5 | Issue 6: Nov – Dec 2024