Correlation Between Preoperative Serum Albumin Levels And Post-Operating Seroma Incidence Of Modified Radical Mastectomy In Breast Cancer Patients
Ngakan Agung Mugi Raharja1*, I Gede Budhi Setiawan2, Ni Gusti Ayu Agung Manik Yuniawaty Wetan2, I Wayan Sudarsa2 , I Made Darmajaya3, and Gede Wirya Kusuma Duarsa4
Abstract
Background: Surgical therapy is still the mainstay of therapy for breast cancer, and modified radical mastectomy (MRM) is the most frequently performed procedure. Seroma formation after breast surgery is a complication that is often found due to the formation of dead space anatomically. A low albumin level indicates an ongoing systemic response and is a one of marker for a seroma. Aim To determine the postoperative complications of modified radical mastectomy in breast cancer patients, namely the incidence of postoperative seroma with preoperative serum albumin levels. Methods: An analytic observational study using a cross sectional study design conducted at the medical record of Prof. Dr. IGNG Ngoerah Denpasar Hospital in January 2019-December 2021. The research subjects were all patients with breast cancer underwent MRM. This study’s data analysis consisted of univariate and bivariate analysis using IBM SPSS version 23. Results: 128 subjects divided into two groups, 30 subjects with seroma and 98 subjects without seroma. Low albumin levels <3.5 gr/dl in the seroma group were found in 18% case and in the group without seromas 39.1%, normal albumin levels > 3.5 gr/dl with seromas occurring in 5.5% respondents and normal albumin levels without seroma found 37.5% respondents. The RR value was 2.4 (CI 95% 1.14-5.34) with a p-value of 0.013. Conclusion: Pre-operative low albumin level < 3.5 gr/dl correlated to high seroma formation after modified radical mastectomy.
Keywords
Albumin; Breast Cancer; Modified radical mastectomy; Seroma
Cite This Article
Raharja, N. A. M., Setiawan, I. B., Wetan, N. G. A. A. M. Y., Sudarsa, I. W., Darmajaya, I. M., Duarsa, G. W. K. (2023). Correlation Between Preoperative Serum Albumin Levels And Post-Operating Seroma Incidence Of Modified Radical Mastectomy In Breast Cancer Patients. International Journal of Scientific Advances (IJSCIA), Volume 4| Issue 3: May-Jun 2023, Pages 410-416, URL: https://www.ijscia.com/wp-content/uploads/2023/06/Volume4-Issue3-May-Jun-No.447-410-416.pdf
Volume 4 | Issue 3: May-Jun 2023
