Covid-19 Coinfection and Dengue Fever in Patients with Myelodysplastic Syndrome: A Case Report

I Wayan Waying Ariatesta Arisova*, Ni Made Renny Anggreni Rena, and I Ketut Agus Somia

Abstract

Introduction: This case report aims to describe the manifestation and management of severe thrombocytopenia in Myelodysplastic Syndrome (MDS) patients with concomitant viral coinfection that also reduce platelet levels. Case Illustration: A female patient aged 77 years came with complaints of gum bleeding, coughing, shortness of breath, fluctuating fever and weakness. Patient was diagnosed with dengue fever with confirmed NS-1 test. One week before admission to the hospital, the patient received 10 units of platelet transfusion. The result of the SARS-CoV-2 Reverse Transcriptase Real Time PCR examination was positive, laboratory examinations showed severe thrombocytopenia and minimal pneumonia on chest X-Ray. The patient was diagnosed with moderate COVID-19 pneumonia, dengue infection and myelodysplastic syndrome. Discussion: Thrombocytopenia is one of the frequently observed manifestations in MDS, dengue infection and COVID-19 due to decreased platelet production in bone marrow and increased platelet destruction in peripheral blood.

Keywords

severe thrombocytopenia; myelodysplastic syndrome; coinfection; dengue; COVID-19

Cite This Article

Arisova, I. W. W. A., Rena, N. M. R. A., Somia, I. K. A. (2023). Covid-19 Coinfection and Dengue Fever in Patients with Myelodysplastic Syndrome: A Case Report. International Journal of Scientific Advances (IJSCIA), Volume 4| Issue 4: Jul-Aug 2023, Pages 664-666, URL: https://www.ijscia.com/wp-content/uploads/2023/08/Volume4-Issue4-Jul-Aug-No.489-664-666.pdf

Volume 4 | Issue 4: Jul-Aug 2023