Diagnosis of Childhood Tuberculosis in Stunted Children Using Chest X-Ray and Mantoux Test: A Literature Review
Evan Aditia Wibisono1, Nur Aisiyah Widjaja2*, Isnin Anang Marhana3
Abstract
Tuberculosis (TB) is a leading cause of pediatric mortality worldwide, with malnutrition, particularly stunting, significantly increasing susceptibility and impacting diagnostic accuracy. Stunting, characterized by chronic undernutrition and zinc deficiency, compromises immune function, elevating levels of pro-inflammatory cytokines and impairing defense against Mycobacterium tuberculosis (MTB). Diagnostic tools like chest X-rays and the Mantoux test demonstrate limitations in stunted children. Chest X-rays, though widely used, lack specificity and depend on the expertise of the reader. The Mantoux test shows reduced sensitivity in malnourished children, with a higher risk of false negatives in severe cases. These findings highlight the need for a cautious interpretation of TB diagnostics in stunted populations and underscore the importance of integrating advanced diagnostic tools for improved accuracy in vulnerable groups.
Keywords
diagnosis of childhood tuberculosis; stunted; chest x-ray; Mantoux.
Cite This Article
Wibisono, E. A., Widjaja, N. A., Marhana, I. A. (2024). Diagnosis of Childhood Tuberculosis in Stunted Children Using Chest X-Ray and Mantoux Test: A Literature Review. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1587-1589, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.773-1587-1589.pdf
Volume 5 | Issue 6: Nov – Dec 2024
