Effects of Continuous Moderate Intensity Training (MICT) and Intermittent Calorie Restriction on Changes in Blood Sugar Levels and The Number of Pancreatic Beta Cells of Female Mice Pancreas (Mus Musculus) on A High Glycemic Index Diet
Belia Nurmaulida Anindito Putri1, Hayuris Kinandita Setiawan2*, Rimbun3, Ira Humairah2 , Alfatih Muhammad Ismail1
Abstract
A diet with a high glycemic index can cause metabolic disease and requires prevention through exercise, diet, or both. This study examined the effect of a combination of Moderate Intensity Continuous Training (MICT) and Intermittent Calorie Restriction (CR) on blood glucose levels and pancreatic beta cells in female mice (Mus musculus) fed with a high glycemic index diet. Using a randomized control trial, four groups were studied: control group (KN), intermittent CR (KI), MICT (KL), and combination group (KK), with interventions including diet reduction and swimming training. KI had the highest change in blood glucose levels after and before intervention, followed by KN, KK, and KL with fasting blood glucose levels and two-hour postprandial glucose levels respectively, KN (26.50 ± 32.42) and (31.25 ± 26.17), KI (44.00 ± 19.84) and (49.40 ± 20.84), KL (-2.67 ± 32.87) and (4.83 ± 15.33), KK (15.67 ± 44.12) and ( 13.50 ± 32.02), with not significantly different. The number of beta cells in each group was KN (74.43 ± 27.45), KI (63.68 ± 34.23), KL (71.08 ± 31.69), and KK (82.22 ± 83, 92), not significantly different. There were no significant changes or effects on blood sugar levels and beta cell numbers in female mice (Mus musculus) fed a high glycemic index diet combined with MICT and intermittent CR.
Keywords
MICT; Calorie restriction; blood glucose; number of pancreatic beta cells.
Cite This Article
Putri, B. N. A., Setiawan, H. K., Rimbun., Humairah, I., Ismail, A. M. (2024). Effects of Continuous Moderate Intensity Training (MICT) and Intermittent Calorie Restriction on Changes in Blood Sugar Levels and The Number of Pancreatic Beta Cells of Female Mice Pancreas (Mus Musculus) on A High Glycemic Index Diet. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1223-1229, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.710-1223-1229.pdf
Volume 5 | Issue 6: Nov – Dec 2024
