Ludwig’s Angina: Clinical Profile and Microbiology with Antibiotic Resistance and Sensitivity at Referral Hospital

Muhamad Saifuddin^*, Sahudi

Abstract

Objective: To assess the distribution of sex and age, comorbidity factors, etiology, management protocol, isolated organisms, antibiotic resistance and sensitivity.

Material and Methods: Retrospective observational study based on medical records in 2007 – 2016 and microbiological examination data from 2012 – 2016.

Results: The proportion of males was greater than females 1.8 (71): 1 (29). Mean age 41 ±SD 16.99. The most comorbidity diagnoses were type 2 diabetes mellitus (DM) 24.5% (27) and the most complications were sepsis 21.8% (24). The most common etiology was odontogenic infection 92%. Patients underwent drainage incisions and were treated with empiric ceftriaxone and metronidazole for an average of 7 days of treatment. Outcomes recovery were 93.7% (102) and were death 5.4% (6). The three most common types of bacteria as the etiology were Enterobacter spp. 32% (9), Streptococcus spp. 25% (7), Staphylococcus spp. 18% (5). Ceftriaxone showed considerable resistance to gram-negative bacteria as well as to gram-positive bacteria (Streptococcus spp.).

Conclusion: The ratio of male to female was 1.8:1 and odontogenic infection was 92%. DM increases the risk of complications of sepsis and prolongs the day of care. A drainage incision should be performed immediately. Gram negative bacteria were the most common bacteria found. The efficacy of using ceftriaxone as empirical therapy needs to be reviewed.

Keywords

Ludwig’s Angina; clinical profile; microbiology; odontogenic infection

Cite This Article

Muhamad, S., Sahudi. (2021). Ludwig’s Angina: Clinical Profile and Microbiology with Antibiotic Resistance and Sensitivity at Referral Hospital. International Journal of Scientific Advances (IJSCIA), Volume 2| Issue 6: Nov-Dec 2021, Pages 951-955 , URL: https://www.ijscia.com/wp-content/uploads/2021/11/Volume2-Issue6-Nov-Dec-No.193-951-955.pdf

Volume 2 | Issue 6: Nov-Dec 2021