Hyperglycemia and Obesity as Risk Factors for Severe Covid-19
Komang Ida Widiayu Radiari Nugraha1, Ida Bagus Ngurah Rai1, I Gede Ketut Sajinadiyasa1*, Wira Gotera2, Ni Wayan Candrawati1, Ida Ayu Jasminarti Dwi Kusumawardani1, Ni Luh Putu Eka Arisanti1, and I Gusti Ngurah Bagus Artana1
Abstract
Background: Obesity and hyperglycemia are common in patients with COVID-19 and are associated with an aggravating risk of COVID-19. This study assesses hyperglycemia and obesity as risk factors for developing severe COVID-19. Method: Analytical observational research with the design used is a matched case-control study. This study divided subjects into two groups according to the dependent variable category of severe COVID-19 as a case and not as severe as a control group. In each group, a history of hyperglycemia and obesity was traced. The analysis includes descriptive tests, bivariate with Chi-Square and multivariate with linear logistic regression using Statistical Product and Service Solutions (SPSS) 26. Result: 126 subjects divided into two groups with 63 subjects each. By age, the COVID-19 group was found to be severe, with an average of 57.9±12.731, and the COVID-19 group was not severe, with an average of 57.53±12.589. Hyperglycemia was associated with severe COVID-19 with a p-result of 0.000 (OR 11.8; CI 95% 3.819-36.456). Obesity was associated with severe COVID-19 with a result of p 0.001 (OR 4.6; CI 95% 1.8 – 11.756). Another covariant factor related to the severity of COVID-19 is Diabetes mellitus (OR: 4.6; CI 95% 2.148–10.137; p=0.028)cardiovascular disease (OR:4.7; 95% CI 1.258-17600; P=0.013),chronic lung disease(OR: 14.5; CI 95% 1.835-115.999).The results of multivariate analysis of Adj Odd Ratio10.038 (95% CI 2.447 – 41.172; P<0.001)and the association with obesity with the Adj Odd Ratio 4.846 (95% CI 1.187 – 19.789; P=0.028). Conclusion: Hyperglycemia and obesity are risk factors for severe COVID-19.
Keywords
severe COVID-19; obesity; hyperglycemia; comorbid
Cite This Article
Nugraha, K. I. W. R., Rai, I. B. N., Sajinadiyasa, I. G. K., Gotera, W., Candrawati, N. W., Kusumawardani, I. A. J. D., Arisanti, N. L. P. E., Artana, I. G. N. B. (2023). Hyperglycemia and Obesity as Risk Factors for Severe Covid-19. International Journal of Scientific Advances (IJSCIA), Volume 4| Issue 3: May-Jun 2023, Pages 367-376, URL: https://www.ijscia.com/wp-content/uploads/2023/05/Volume4-Issue3-May-Jun-No.441-367-376.pdf
Volume 4 | Issue 3: May-Jun 2023
