Relationship between Comorbidity and Survival of Cervical Cancer: A Literature Review
Jihan Rania1, Abdul Khairul Rizki Purba2*, Avilia Ramadhani Avidar1
Abstract
Cervical cancer is characterized as a tumor that forms in the lower section of the uterus, with persistent infection by high-risk HPV being the primary cause. Data from the WHO indicates that cervical cancer is the fourth most common cancer among women. In 2020, approximately 604,000 new cases were diagnosed, resulting in 342,000 deaths. Survival outcomes for cervical cancer patients vary based on several factors, including cancer stage, type, grade, age, recurrence, and the patient’s overall health, particularly the presence of comorbidities. Comorbidity refers to the coexistence of an additional condition alongside a primary or index disease, which can either directly affect the prognosis of the primary condition or indirectly influence treatment decisions. In cancer patients, comorbidities can play a significant role in influencing disease progression, stage at diagnosis, treatment strategies, and clinical outcomes. Several studies have shown a significant relationship between comorbidities and survival in cervical cancer patients. However, other research has reported no significant association between comorbidities and cervical cancer survival. These differences in findings can be attributed to various factors, including variations in inclusion and exclusion criteria, differences in how comorbidities are measured, and variations in control variables such as age, treatment modalities, ethnicity, and cancer stage.
Keywords
cervical cancer; survival; comorbidity.
Cite This Article
Rania, J., Purba, A. K. R., Avidar, A. R. (2024). Relationship between Comorbidity and Survival of Cervical Cancer: A Literature Review. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1294-1298, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.721-1294-1298.pdf
Volume 5 | Issue 6: Nov – Dec 2024
