Beta Cell Death Mechanism in Type 2 Diabetes: An Overview Mikhael Akbar Rizky Siagian1, Bellinda Zalzabillah Tazkira1 and Lilik Herawati2* Abstract Beta cell failure is central to the development and progression of type 2 diabetes (T2D). This article examines the mechanism of beta cell death in T2D. Chronic hyperglycemia and