Differentiating Malignant and Benign Lesion in Thyroid, Is There Any New Marker? Debby Victoria Arief, Nila Kurniasari* and Ridholia Abstract The most common malignancy of the endocrine gland is papillary thyroid carcinoma (90% of endocrine malignancy). In many cases, the tumor showed borderline morphology between benign lesions and characteristics of