The Comparison of Clinical Outcomes Between DJ Stent Insertion and Percutaneous Nephrostomy in Patients with Obstructive Uropathy due to Cervical Cancer

I Dewa Gede Sidan Agung Mahendra1, Kadek Budi Santosa2*, Anak Agung Gde Oka2, and I Wayan Gede Artawan Eka Putra3

Abstract

Background: Metastatic cervical cancer into the ureter may lead to obstructive uropathy due to mechanical ureteral blockage. The insertion of a double J (DJ) stent and percutaneous nephrostomy (PCN) are some options that can be offered to the patients, but until now the comparison between these two procedures is still debated. Aim: The aim of the study is to compare the clinical outcomes of DJ stent insertion and PCN in the management of uropathy obstructive secondary to cervical cancer. Materials and Methods: This study is an analytical observation with a retrospective cohort design. We analyzed the difference in clinical outcomes between the two procedures such as 24-hour renal function, the number of visits due to procedure or device related complications, quality of life and overall survival in patients with stage 3B cervical cancer. Results: We collected 108 patients with uropathy obstructive secondary to stage 3B cervical cancer from January 2019 to July 2021, of which 54 underwent DJ stents insertion and 54 underwent PCN. There was no difference in the improvement of renal function between the two procedures (p=0.184), as well as on the parameters of quality of life (p=0,909) and overall survival (p=0,582). We found a significant difference in patient visits to the hospital due to procedure related complications. Patients who have a DJ stent inserted are more often come to the hospital because of fever and pain compared to patients who have PCN procedures (p=0,027). Conclusion: Percutaneous nephrostomy is superior to DJ stent insertion in terms of procedure related complications. However, an individualized approach regarding the most appropriate procedure in palliative care patients should be recommended.

Keywords

cervical cancer; DJ stent; percutaneous nephrostomy; obstructive uropathy

Cite This Article

Mahendra, I. D. G. S. A., Santosa, K. B., Oko, A. A. G., Putra, I. W. G. A. E. (2023). The Comparison of Clinical Outcomes Between Dj Stent Insertion and Percutaneous Nephrostomy in Patients with Obstructive Uropathy due to Cervical Cancer. International Journal of Scientific Advances (IJSCIA), Volume 4| Issue 2: Mar-Apr 2023, Pages 1ุ77-182, URL: https://www.ijscia.com/wp-content/uploads/2023/04/Volume4-Issue2-Mar-Apr-No.414-177-182.pdf

Volume 4 | Issue 2: Mar-Apr 2023