The Correlation Between Increased Transaminase Levels with Maternal and Neonatal Outcomes in Severe Preeclampsia at Dr. Soetomo General Academic Hospital Surabaya: A Retrospective Analysis Study
Marsha Ega Nafila1*, Agus Sulistyono2, Mahendra Tri Arif Sampurna3, Manggala Pasca Wardana4
Abstract
Introduction: Preeclampsia is one of the highest causes of maternal mortality in Indonesia. The latest survey data shows Indonesia’s Maternal Mortality Rate (MMR) is 305/100,000 live births. The cause of most maternal deaths in Indonesia occurs due to hypertension, preeclampsia, eclampsia, bleeding, and infection. Preeclampsia is a condition that can affect multiple systems of the body. An unusual vascular reaction to the placenta’s growth is remarkable, leading to higher levels of systemic vascular resistance. This study aims to determine the correlation between increased transaminase levels with maternal and neonatal outcomes in severe preeclampsia at Dr. Soetomo General Academic Hospital Surabaya. Methods: This study is a retrospective analysis study at the Obstetrics and Gynecology department at Dr. Soetomo General Academic Hospital Surabaya from January 2022 – December 2022. The sampling method of this research is by taking laboratory tests of abnormal and normal transaminase levels data before delivery from the medical records of pregnant women with severe preeclampsia. The sample size was determined by total sampling, which resulted in 165 maternal data records. Results: A significant correlation was found between increased transaminase levels and maternal mortality. Also, a significant correlation was found between transaminase levels with gestational age and baby birth weight. Conclusions: Most patients with severe preeclampsia were found to have normal SGOT and SGPT levels. A significant correlation was found between increased transaminase levels and maternal. A significant correlation was found between increased transaminase levels with gestational age and baby birth weight.
Keywords
severe preeclampsia; increased transaminase; maternal and neonatal outcome.
Cite This Article
Nafila, M. E., Sulistyono, A., Sampurna, M. T. A., Wardana, M. P. (2024). The Correlation Between Increased Transaminase Levels with Maternal and Neonatal Outcomes in Severe Preeclampsia at Dr. Soetomo General Academic Hospital Surabaya: A Retrospective Analysis Study. International Journal of Scientific Advances (IJSCIA), Volume 5| Issue 6: Nov-Dec 2024, Pages 1309-1318, URL: https://www.ijscia.com/wp-content/uploads/2024/12/Volume5-Issue6-Nov-Dec-No.724-1309-1318.pdf
Volume 5 | Issue 6: Nov – Dec 2024
