The Shocking Truth: A Case Study of Allergic Reaction Leading to Heart Attack
Yohana Ratih Dwi Pusaparini1*, Dimas R. Balti2, Trifena2
Abstract
Background: Anaphylactic shock is a symptom of a severe allergic reaction that occurs after exposure to an allergen. Manifestations of anaphylactic shock can occur in various organs such as the cardiovascular system. Kounis syndrome (KS) is an acute coronary syndrome (ACS) related to allergic anaphylactic reactions triggered by the release of inflammation cells and mediators. Case Description: A 35-year-old male presented with a problem on his left leg skin. Examination revealed a red and edematous wound on his left calf, accompanied by pain and tenderness. He was then referred to a dermatologist by the on-duty doctor. Further diagnosis revealed cellulitis of the left leg, and he received intravenous meropenem 1 gram and oral clindamycin 300 mg. Four hours after the administration of intravenous meropenem and oral clindamycin, the patient complained of chest discomfort associated with palpitations, shortness of breath, nausea, and vomiting. His physical examination was remarkable for a shock with hypoxia and features of an anaphylactic reaction. Conclusion: We report a rare case of Kounis syndrome due to a drug allergy causing anaphylactic shock reaction. The treatments depend on the cause and symptoms of the patient.
Keywords
allergic reactions; acute coronary syndrome; Kounis syndrome.
Cite This Article
Pusaparini, Y. R. D., Balti, D. R., Trifena,. (2025). The Shocking Truth: A Case Study of Allergic Reaction Leading to Heart Attack. International Journal of Scientific Advances (IJSCIA), Volume 6| Issue 2: Mar-Apr 2025, Pages 261-264 URL: https://www.ijscia.com/wp-content/uploads/2025/03/Volume6-Issue2-Mar-Apr-No.851-261-264.pdf
Volume 6 | Issue 2: Mar – Apr 2025
